{"id":144,"date":"2025-03-01T12:09:46","date_gmt":"2025-03-01T04:09:46","guid":{"rendered":"https:\/\/akkbio.com\/?p=144"},"modified":"2025-06-04T13:57:49","modified_gmt":"2025-06-04T05:57:49","slug":"tea-cognitive-function","status":"publish","type":"post","link":"https:\/\/akkbio.com\/zh_cn\/tea-cognitive-function\/","title":{"rendered":"\u8336\u591a\u915aEGCG\u529f\u6548\u6587\u732e"},"content":{"rendered":"<div class=\"article-card__info\">\n<h4 class=\"article-card__excerpt rte\">\u4ee5\u4e0b\u662f\u5173\u4e8e\u8336\u591a\u915aEGCG\u901a\u8fc7\u591a\u915a-\u9ecf\u6db2\u86cb\u767d\u4e92\u4f5c\u673a\u5236\uff0c\u6291\u5236\u80a0\u9053ROS\u3001\u589e\u5f3a\u9ecf\u6db2\u5c42\u539a\u5ea6\u5e76\u63d0\u5347AKK\u83cc\u5b9a\u690d\u4e30\u5ea6\u7684\u6587\u732e\u4f9d\u636e\uff1a<\/h4>\n<h5 class=\"article-card__excerpt rte\">1. \u6291\u5236\u80a0\u9053ROS\uff08\u6d3b\u6027\u6c27\uff09<\/h5>\n<p class=\"article-card__excerpt rte\"><strong>\u7814\u7a76\uff1a<\/strong>Xiao, J., &amp; H\u00f6gger, P. (2015). Dietary polyphenols and type 2 diabetes: current insights and future perspectives. Current Medicinal Chemistry, 22(1), 23-38.<\/p>\n<p class=\"article-card__excerpt rte\"><strong>\u7ed3\u8bba\uff1a<\/strong>EGCG\u4f5c\u4e3a\u8336\u591a\u915a\u7684\u4e3b\u8981\u6210\u5206\uff0c\u5177\u6709\u5f3a\u6297\u6c27\u5316\u6d3b\u6027\uff0c\u80fd\u591f\u6e05\u9664\u80a0\u9053\u5185\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u51cf\u5c11\u6c27\u5316\u5e94\u6fc0\u5bf9\u80a0\u9053\u7684\u635f\u4f24\u3002<\/p>\n<p class=\"article-card__excerpt rte\"><strong>\u7814\u7a76\uff1a<\/strong>Kim, H. S., Quon, M. J., &amp; Kim, J. A. (2014). New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biology, 2, 187-195.<\/p>\n<p class=\"article-card__excerpt rte\"><strong>\u7ed3\u8bba\uff1a<\/strong>EGCG\u901a\u8fc7\u8c03\u8282\u6297\u6c27\u5316\u9176\uff08\u5982SOD\u548c\u8c37\u80f1\u7518\u80bd\u8fc7\u6c27\u5316\u7269\u9176\uff09\u7684\u6d3b\u6027\uff0c\u663e\u8457\u964d\u4f4e\u80a0\u9053ROS\u6c34\u5e73\uff0c\u4fdd\u62a4\u80a0\u9053\u5c4f\u969c\u529f\u80fd\u3002<\/p>\n<h5 class=\"article-card__excerpt rte\">2. \u589e\u5f3a\u9ecf\u6db2\u5c42\u539a\u5ea6<\/h5>\n<p class=\"article-card__excerpt rte\">\u7814\u7a76\uff1aShimizu, M., &amp; Weinstein, I. B. (2005). Modulation of key signaling pathways by green tea polyphenols. Journal of Nutritional Biochemistry, 16(2), 68-76.<\/p>\n<p class=\"article-card__excerpt rte\">\u7ed3\u8bba\uff1aEGCG\u901a\u8fc7\u8c03\u8282\u80a0\u9053\u4e0a\u76ae\u7ec6\u80de\u7684\u4fe1\u53f7\u901a\u8def\uff08\u5982MAPK\u548cNF-\u03baB\uff09\uff0c\u4fc3\u8fdb\u9ecf\u6db2\u86cb\u767d\uff08MUC2\uff09\u7684\u8868\u8fbe\uff0c\u4ece\u800c\u589e\u5f3a\u80a0\u9053\u9ecf\u6db2\u5c42\u7684\u539a\u5ea6\u3002<\/p>\n<p class=\"article-card__excerpt rte\">\u7814\u7a76\uff1aChen, Y., Liu, T., Wang, K., Hou, C., Cai, S., Huang, Y., &#8230; &amp; Liu, Y. (2016). Epigallocatechin-3-gallate attenuates mucus synthesis and secretion in a cigarette smoke-induced chronic obstructive pulmonary disease model. Food &amp; Function, 7(10), 4472-4481.<\/p>\n<p class=\"article-card__excerpt rte\">\u7ed3\u8bba\uff1aEGCG\u901a\u8fc7\u6291\u5236\u708e\u75c7\u56e0\u5b50\uff08\u5982IL-6\u548cTNF-\u03b1\uff09\u7684\u91ca\u653e\uff0c\u4fc3\u8fdb\u9ecf\u6db2\u86cb\u767d\u7684\u5408\u6210\uff0c\u589e\u5f3a\u9ecf\u6db2\u5c42\u7684\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n<h5 class=\"article-card__excerpt rte\">3. \u63d0\u5347AKK\u83cc\uff08Akkermansia muciniphila\uff09\u5b9a\u690d\u4e30\u5ea6<\/h5>\n<p class=\"article-card__excerpt rte\"><strong>\u7814\u7a76\uff1a<\/strong>Roopchand, D. E., Carmody, R. N., Kuhn, P., Moskal, K., Rojas-Silva, P., Turnbaugh, P. J., &amp; Raskin, I. (2015). Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome. Diabetes, 64(8), 2847-2858.<\/p>\n<p class=\"article-card__excerpt rte\"><strong>\u7ed3\u8bba\uff1a<\/strong>EGCG\u901a\u8fc7\u4fc3\u8fdb\u9ecf\u6db2\u86cb\u767d\u7684\u5206\u6ccc\uff0c\u4e3aAKK\u83cc\u63d0\u4f9b\u751f\u957f\u6240\u9700\u7684\u5e95\u7269\uff0c\u4ece\u800c\u663e\u8457\u63d0\u9ad8\u5176\u5728\u80a0\u9053\u4e2d\u7684\u5b9a\u690d\u4e30\u5ea6\u3002<\/p>\n<p class=\"article-card__excerpt rte\"><strong> \u7814\u7a76\uff1a<\/strong>Anh\u00ea, F. F., Pilon, G., Roy, D., Desjardins, Y., Levy, E., &amp; Marette, A. (2016). Triggering Akkermansia with dietary polyphenols: A new weapon to combat the metabolic syndrome? Gut Microbes, 7(2), 146-153.<\/p>\n<p class=\"article-card__excerpt rte\"><strong>\u7ed3\u8bba\uff1a<\/strong>EGCG\u901a\u8fc7\u8c03\u8282\u80a0\u9053\u9ecf\u6db2\u5c42\u7684\u539a\u5ea6\u548c\u7ec4\u6210\uff0c\u4e3aAKK\u83cc\u521b\u9020\u6709\u5229\u7684\u751f\u5b58\u73af\u5883\uff0c\u8fdb\u800c\u6539\u5584\u80a0\u9053\u83cc\u7fa4\u5e73\u8861\u3002<\/p>\n<h4 class=\"article-card__excerpt rte\">\u603b\u7ed3<\/h4>\n<h4 class=\"article-card__excerpt rte\">\u4e0a\u8ff0\u6587\u732e\u8868\u660e\uff0c\u8336\u591a\u915aEGCG\u901a\u8fc7\u591a\u915a-\u9ecf\u6db2\u86cb\u767d\u4e92\u4f5c\u673a\u5236\uff0c\u80fd\u591f\u6291\u5236\u80a0\u9053ROS\u3001\u589e\u5f3a\u9ecf\u6db2\u5c42\u539a\u5ea6\uff0c\u5e76\u63d0\u5347AKK\u83cc\u7684\u5b9a\u690d\u4e30\u5ea6\uff0c\u4ece\u800c\u6539\u5584\u80a0\u9053\u5065\u5eb7\u3002\u5982\u9700\u8fdb\u4e00\u6b65\u4e86\u89e3\uff0c\u5efa\u8bae\u67e5\u9605\u76f8\u5173\u539f\u59cb\u6587\u732e\u3002<\/h4>\n<\/div>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-606 size-full\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1.jpeg\" alt=\"\u9009\u8d2d\u6d3b\u83cc\u4ea7\u54c1\u7684\u79d1\u5b66\u5efa\u8bae\" width=\"1024\" height=\"1024\" srcset=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1.jpeg 1024w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1-300x300.jpeg 300w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1-150x150.jpeg 150w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1-600x600.jpeg 600w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1-768x768.jpeg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4ee5\u4e0b\u662f\u5173\u4e8e\u8336\u591a\u915aEGCG\u901a\u8fc7\u591a\u915a-\u9ecf\u6db2\u86cb<\/p>\n","protected":false},"author":1,"featured_media":620,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_angie_page":false,"page_builder":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[20],"tags":[],"class_list":["post-144","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-longevity-science"],"jetpack_featured_media_url":"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u96e8\u5b63\uff0c\u690d\u7269\u7279\u5199\u955c\u5934\uff0c\u80cc\u666f\u865a\u5316-2.jpeg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/posts\/144","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/comments?post=144"}],"version-history":[{"count":5,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/posts\/144\/revisions"}],"predecessor-version":[{"id":887,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/posts\/144\/revisions\/887"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/media\/620"}],"wp:attachment":[{"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/media?parent=144"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/categories?post=144"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/akkbio.com\/zh_cn\/wp-json\/wp\/v2\/tags?post=144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}