{"id":25,"date":"2025-03-01T10:03:05","date_gmt":"2025-03-01T02:03:05","guid":{"rendered":"https:\/\/akkbio.com\/?page_id=25"},"modified":"2025-03-26T16:15:08","modified_gmt":"2025-03-26T08:15:08","slug":"science","status":"publish","type":"page","link":"https:\/\/akkbio.com\/en\/science\/","title":{"rendered":"Sience Evidence"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"25\" class=\"elementor elementor-25\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"wd-negative-gap elementor-element elementor-element-ea34ae5 wd-section-stretch e-flex e-con-boxed e-con e-parent\" data-id=\"ea34ae5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_video_link&quot;:&quot;https:\\\/\\\/akkbio.com\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Science_\\u2013_PAREMINA.mp4&quot;,&quot;background_play_on_mobile&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-background-video-container\">\n\t\t\t\t\t\t\t<video class=\"elementor-background-video-hosted\" role=\"presentation\" autoplay muted playsinline loop><\/video>\n\t\t\t\t\t<\/div>\t\t<div class=\"elementor-element elementor-element-445b086 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"445b086\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Sience Evidence<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-cbc46aa e-flex e-con-boxed e-con e-parent\" data-id=\"cbc46aa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-10d7f38 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"10d7f38\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInLeft&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f42aaa wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"8f42aaa\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h2 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">AKM\/AKK BIO Tech<\/h2> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-399ea14 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"399ea14\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b8dc0c1 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"b8dc0c1\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Since its discovery in 2004, over 20 years of research and thousands of laboratory and clinical research articles have accumulated a great deal of scientific evidence for the entry of AKK bacterial products into our lives.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-a805a4f e-flex e-con-boxed e-con e-parent\" data-id=\"a805a4f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-49fbe2e e-con-full e-flex e-con e-child\" data-id=\"49fbe2e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-75fc269 elementor-invisible elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"75fc269\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u96e8\u5b63\uff0c\u690d\u7269\u7279\u5199\u955c\u5934\uff0c\u80cc\u666f\u865a\u5316-1-800x600.jpeg\" class=\"attachment-800x600 size-800x600\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d2ef6c6 e-con-full e-flex e-con e-child\" data-id=\"d2ef6c6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-89005c1 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"89005c1\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What are second generation probiotics? How are they different from first generation probiotics?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fed7a8d elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"fed7a8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d3e1f0 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"9d3e1f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Second-generation probiotics, also known as new-generation probiotics, are new types of probiotics screened and cultivated through modern biotechnological means on the basis of first-generation probiotics (mainly lactobacilli and bifidobacteria). Compared with the first generation of probiotics, the second generation of probiotics has significantly improved in terms of efficacy, safety and adaptability, and is able to regulate the micro-ecological balance of the intestinal tract, enhance immunity, improve the function of the digestive system, and so on, to provide more comprehensive protection for human health.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-c1c9323 e-flex e-con-boxed e-con e-parent\" data-id=\"c1c9323\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a9076ea wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"a9076ea\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What specific strains are listed as second generation probiotics?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ce1253 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"1ce1253\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\t<p>Currently, the main strains classified as second-generation probiotics include the following:<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-d922d21 e-grid e-con-boxed elementor-invisible e-con e-parent\" data-id=\"d922d21\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c853c6e elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"c853c6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bacteria\" viewbox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path 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class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tClostridium butyricum \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tA probiotic that produces caseinate, one of the representatives of the second generation of probiotics.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c91b86 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"3c91b86\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bacteria\" viewbox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path 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class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tAkkermansia muciniphila\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tIt has received much attention in recent years and is closely related to the gut mucus layer and metabolic health.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e2387b elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"5e2387b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  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class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tFaecalibacterium prausnitzii \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tOne of the dominant bacteria in the intestinal tract with significant anti-inflammatory properties.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4b7dec elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"c4b7dec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  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class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tSome strains of the genus Bifidobacterium\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tBifidobacterium longum subsp. longum, for example, is an upgraded version of traditional probiotics.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b66183 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"1b66183\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bacteria\" viewbox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M272.35,226.4A17.71,17.71,0,0,0,281.46,203l-4-9.08a121.29,121.29,0,0,1,12.36-3.08A83.34,83.34,0,0,0,323.57,177l10,9a17.76,17.76,0,1,0,23.92-26.27l-9.72-8.76a83.12,83.12,0,0,0,11.65-48.18l11.85-3.51a17.73,17.73,0,1,0-10.15-34l-11.34,3.36a84,84,0,0,0-36.38-35.57l2.84-10.85a17.8,17.8,0,0,0-34.47-8.93l-2.82,10.78a83.25,83.25,0,0,0-16.74,1.1C250.83,27,240,30.22,229.1,33.39l-3.38-9.46a17.8,17.8,0,0,0-33.56,11.89l3.49,9.8a286.74,286.74,0,0,0-43.94,23.57l-6.32-8.43a17.9,17.9,0,0,0-24.94-3.6A17.69,17.69,0,0,0,116.84,82l6.45,8.61a286.59,286.59,0,0,0-34.95,35.33l-8.82-6.42a17.84,17.84,0,0,0-24.89,3.86,17.66,17.66,0,0,0,3.88,24.77l8.88,6.47a286.6,286.6,0,0,0-23,43.91l-10.48-3.59a17.73,17.73,0,1,0-11.59,33.52L32.67,232c-2.79,10-5.79,19.84-7.52,30.22a83.16,83.16,0,0,0-.82,19l-11.58,3.43a17.73,17.73,0,1,0,10.13,34l11.27-3.33a83.51,83.51,0,0,0,36.39,35.43l-2.88,11.06a17.81,17.81,0,0,0,34.48,8.92l2.87-11c1,0,2.07.26,3.1.26a83.39,83.39,0,0,0,45.65-13.88l8.59,8.8a17.77,17.77,0,0,0,25.56-24.7l-9.14-9.37a83.41,83.41,0,0,0,12.08-31.05,119.08,119.08,0,0,1,3.87-15.53l9,4.22a17.74,17.74,0,1,0,15.15-32.09l-8.8-4.11c.67-1,1.2-2.08,1.9-3.05a119.89,119.89,0,0,1,7.87-9.41,121.73,121.73,0,0,1,11.65-11.4,119.49,119.49,0,0,1,9.94-7.82c1.12-.77,2.32-1.42,3.47-2.15l3.92,8.85a17.86,17.86,0,0,0,16.32,10.58A18.14,18.14,0,0,0,272.35,226.4ZM128,256a32,32,0,1,1,32-32A32,32,0,0,1,128,256Zm80-96a16,16,0,1,1,16-16A16,16,0,0,1,208,160Zm431.26,45.3a17.79,17.79,0,0,0-17.06-12.69,17.55,17.55,0,0,0-5.08.74l-11.27,3.33a83.61,83.61,0,0,0-36.39-35.43l2.88-11.06a17.81,17.81,0,0,0-34.48-8.91l-2.87,11c-1,0-2.07-.26-3.1-.26a83.32,83.32,0,0,0-45.65,13.89l-8.59-8.81a17.77,17.77,0,0,0-25.56,24.7l9.14,9.37a83.28,83.28,0,0,0-12.08,31.06,119.34,119.34,0,0,1-3.87,15.52l-9-4.22a17.74,17.74,0,1,0-15.15,32.09l8.8,4.11c-.67,1-1.2,2.08-1.89,3.05a117.71,117.71,0,0,1-7.94,9.47,119,119,0,0,1-11.57,11.33,121.59,121.59,0,0,1-10,7.83c-1.12.77-2.32,1.42-3.47,2.15l-3.92-8.85a17.86,17.86,0,0,0-16.32-10.58,18.14,18.14,0,0,0-7.18,1.5A17.71,17.71,0,0,0,358.54,309l4,9.08a118.71,118.71,0,0,1-12.36,3.08,83.34,83.34,0,0,0-33.77,13.9l-10-9a17.77,17.77,0,1,0-23.92,26.28l9.72,8.75a83.12,83.12,0,0,0-11.65,48.18l-11.86,3.51a17.73,17.73,0,1,0,10.16,34l11.34-3.36A84,84,0,0,0,326.61,479l-2.84,10.85a17.8,17.8,0,0,0,34.47,8.93L361.06,488a83.3,83.3,0,0,0,16.74-1.1c11.37-1.89,22.24-5.07,33.1-8.24l3.38,9.46a17.8,17.8,0,0,0,33.56-11.89l-3.49-9.79a287.66,287.66,0,0,0,43.94-23.58l6.32,8.43a17.88,17.88,0,0,0,24.93,3.6A17.67,17.67,0,0,0,523.16,430l-6.45-8.61a287.37,287.37,0,0,0,34.95-35.34l8.82,6.42a17.76,17.76,0,1,0,21-28.63l-8.88-6.46a287.17,287.17,0,0,0,23-43.92l10.48,3.59a17.73,17.73,0,1,0,11.59-33.52L607.33,280c2.79-10,5.79-19.84,7.52-30.21a83.27,83.27,0,0,0,.82-19.05l11.58-3.43A17.7,17.7,0,0,0,639.26,205.3ZM416,416a32,32,0,1,1,32-32A32,32,0,0,1,416,416Z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tSome strains of the genus Lactobacillus \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tLactobacillus acidophilus, for example, still has an important place among second-generation probiotics.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-204d926 e-flex e-con-boxed e-con e-parent\" data-id=\"204d926\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a1d226c elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"a1d226c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\tThese strains are not all newly discovered microorganisms, but have been endowed with more defined health benefits through scientific research, distinguishing them from traditional first-generation probiotics.\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-6ac8ee7 wd-section-stretch e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"6ac8ee7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-32c5cef e-con-full e-flex e-con e-child\" data-id=\"32c5cef\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ee96a4 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"9ee96a4\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What specific strains are listed as second generation probiotics?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d2bbd7 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"0d2bbd7\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e0543c elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"5e0543c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\tThe efficacy of second-generation probiotics is more diverse and targeted, mainly in the following areas:\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c7dba35 e-con-full e-grid e-con e-child\" data-id=\"c7dba35\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e5152bf elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"e5152bf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bacon\" viewbox=\"0 0 576 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M218.92 336.39c34.89-34.89 44.2-59.7 54.05-86 10.61-28.29 21.59-57.54 61.37-97.34s69.05-50.77 97.35-61.38c23.88-9 46.64-17.68 76.79-45.37L470.81 8.91a31 31 0 0 0-40.18-2.83c-13.64 10.1-25.15 14.39-41 20.3C247 79.52 209.26 191.29 200.65 214.1c-29.75 78.83-89.55 94.68-98.72 98.09-24.86 9.26-54.73 20.38-91.07 50.36C-3 374-3.63 395 9.07 407.61l35.76 35.51C80 410.52 107 400.15 133 390.39c26.27-9.84 51.06-19.12 85.92-54zm348-232l-35.75-35.51c-35.19 32.63-62.18 43-88.25 52.79-26.26 9.85-51.06 19.16-85.95 54s-44.19 59.69-54 86C292.33 290 281.34 319.22 241.55 359s-69 50.73-97.3 61.32c-23.86 9-46.61 17.66-76.72 45.33l37.68 37.43a31 31 0 0 0 40.18 2.82c13.6-10.06 25.09-14.34 40.94-20.24 142.2-53 180-164.1 188.94-187.69C405 219.18 464.8 203.3 474 199.86c24.87-9.27 54.74-20.4 91.11-50.41 13.89-11.4 14.52-32.45 1.82-45.05z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tRegulates intestinal microecological balance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tThe diversity and stability of the intestinal flora is maintained by competitively inhibiting the growth of harmful bacteria. For example, Clostridium typhimurium inhibits the colonization of harmful bacteria, and Ackermannia improves the intestinal environment by regulating the thickness of the mucus layer.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8142e1 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"c8142e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bahai\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M496.25 202.52l-110-15.44 41.82-104.34c6.67-16.64-11.6-32.18-26.59-22.63L307.44 120 273.35 12.82C270.64 4.27 263.32 0 256 0c-7.32 0-14.64 4.27-17.35 12.82l-34.09 107.19-94.04-59.89c-14.99-9.55-33.25 5.99-26.59 22.63l41.82 104.34-110 15.43c-17.54 2.46-21.68 26.27-6.03 34.67l98.16 52.66-74.48 83.54c-10.92 12.25-1.72 30.93 13.29 30.93 1.31 0 2.67-.14 4.07-.45l108.57-23.65-4.11 112.55c-.43 11.65 8.87 19.22 18.41 19.22 5.15 0 10.39-2.21 14.2-7.18l68.18-88.9 68.18 88.9c3.81 4.97 9.04 7.18 14.2 7.18 9.54 0 18.84-7.57 18.41-19.22l-4.11-112.55 108.57 23.65c17.36 3.76 29.21-17.2 17.35-30.49l-74.48-83.54 98.16-52.66c15.64-8.39 11.5-32.2-6.04-34.66zM338.51 311.68l-51.89-11.3 1.97 53.79L256 311.68l-32.59 42.49 1.96-53.79-51.89 11.3 35.6-39.93-46.92-25.17 52.57-7.38-19.99-49.87 44.95 28.62L256 166.72l16.29 51.23 44.95-28.62-19.99 49.87 52.57 7.38-46.92 25.17 35.61 39.93z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tstrengthen immunity\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tStimulates immune cell activity and increases the body's resistance to pathogens. For example, Lactobacillus acidophilus enhances the immune response and helps fight infections.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f41baf2 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"f41baf2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-virus-slash\" viewbox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M114,227.6H92.4C76.7,227.6,64,240.3,64,256s12.7,28.4,28.4,28.4H114c50.7,0,76.1,61.3,40.2,97.1L139,396.8 c-11.5,10.7-12.2,28.7-1.6,40.2s28.7,12.2,40.2,1.6c0.5-0.5,1.1-1,1.6-1.6l15.2-15.2c35.8-35.8,97.1-10.5,97.1,40.2v21.5 c0,15.7,12.8,28.4,28.5,28.4c15.7,0,28.4-12.7,28.4-28.4V462c0-26.6,17-45.9,38.2-53.4l-244.5-189 C133.7,224.7,123.9,227.5,114,227.6z M617,505.8l19.6-25.3c5.4-7,4.2-17-2.8-22.5L470.6,332c4.2-25.4,24.9-47.5,55.4-47.5h21.5 c15.7,0,28.4-12.7,28.4-28.4s-12.7-28.4-28.4-28.4H526c-50.7,0-76.1-61.3-40.2-97.1l15.2-15.3c10.7-11.5,10-29.5-1.6-40.2 c-10.9-10.1-27.7-10.1-38.6,0l-15.2,15.2c-35.8,35.8-97.1,10.5-97.1-40.2V28.5C348.4,12.7,335.7,0,320,0 c-15.7,0-28.4,12.7-28.4,28.4V50c0,50.7-61.3,76.1-97.1,40.2L179.2,75c-11.1-11.1-29.4-10.6-40.5,0.5L45.5,3.4 c-7-5.4-17-4.2-22.5,2.8L3.4,31.5c-5.4,7-4.2,17,2.8,22.5l588.4,454.7C601.5,514.1,611.6,512.8,617,505.8z M335.4,227.5l-62.9-48.6 c4.9-1.8,10.2-2.8,15.4-2.9c26.5,0,48,21.5,48,48C336,225.2,335.5,226.3,335.4,227.5z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tImprovement of the functioning of the digestive system\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tIt promotes food digestion and absorption, and relieves constipation, diarrhea and other indigestion symptoms. Bifidobacterium longum bifidum performs particularly well in this regard.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d0faa56 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"d0faa56\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-asterisk\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M478.21 334.093L336 256l142.21-78.093c11.795-6.477 15.961-21.384 9.232-33.037l-19.48-33.741c-6.728-11.653-21.72-15.499-33.227-8.523L296 186.718l3.475-162.204C299.763 11.061 288.937 0 275.48 0h-38.96c-13.456 0-24.283 11.061-23.994 24.514L216 186.718 77.265 102.607c-11.506-6.976-26.499-3.13-33.227 8.523l-19.48 33.741c-6.728 11.653-2.562 26.56 9.233 33.037L176 256 33.79 334.093c-11.795 6.477-15.961 21.384-9.232 33.037l19.48 33.741c6.728 11.653 21.721 15.499 33.227 8.523L216 325.282l-3.475 162.204C212.237 500.939 223.064 512 236.52 512h38.961c13.456 0 24.283-11.061 23.995-24.514L296 325.282l138.735 84.111c11.506 6.976 26.499 3.13 33.227-8.523l19.48-33.741c6.728-11.653 2.563-26.559-9.232-33.036z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tanti-inflammatory effect\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\tBy producing anti-inflammatory substances, it relieves intestinal inflammation and prevents diseases such as inflammatory bowel disease. Clostridium Pullorum is a prime example of this effect.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5484cf8 elementor-view-default elementor-position-block-start elementor-mobile-position-block-start elementor-widget elementor-widget-icon-box\" data-id=\"5484cf8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<span  class=\"elementor-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-exchange-alt\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 168v-16c0-13.255 10.745-24 24-24h360V80c0-21.367 25.899-32.042 40.971-16.971l80 80c9.372 9.373 9.372 24.569 0 33.941l-80 80C409.956 271.982 384 261.456 384 240v-48H24c-13.255 0-24-10.745-24-24zm488 152H128v-48c0-21.314-25.862-32.08-40.971-16.971l-80 80c-9.372 9.373-9.372 24.569 0 33.941l80 80C102.057 463.997 128 453.437 128 432v-48h360c13.255 0 24-10.745 24-24v-16c0-13.255-10.745-24-24-24z\"><\/path><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tRegulation of metabolism\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<p class=\"elementor-icon-box-description\">\n\t\t\t\t\t\t\uf0b7 affects energy metabolism and lipid metabolism and improves metabolic diseases such as obesity and diabetes. Ackermann's bacteria are closely associated with the improvement of metabolic diseases.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b412358 e-con-full e-flex e-con e-child\" data-id=\"b412358\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9054670 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"9054670\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<p class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Summarize<\/p> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f606f6b elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"f606f6b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Second-generation probiotics are new probiotics developed on the basis of first-generation probiotics, and the representative strains include Clostridium Typhimurium, Clostridium Ackermannii, Clostridium Pullorum, as well as some strains of Bifidobacterium and Lactobacillus. Their efficacy covers the regulation of intestinal microecology, enhancement of immunity, improvement of digestive function, anti-inflammatory and metabolic regulation, etc. Compared with traditional probiotics, they are more diversified and precise, and are able to provide more comprehensive support for human health.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-226ea29 e-flex e-con-boxed e-con e-parent\" data-id=\"226ea29\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5bfdb90 e-con-full e-flex e-con e-child\" data-id=\"5bfdb90\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bcd96a6 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"bcd96a6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What are first generation probiotics?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7f1a873 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"7f1a873\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af8ffcd elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"af8ffcd\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\tFirst-generation probiotics refer to the earliest probiotic strains discovered and applied, mainly including lactobacilli (e.g. Lactobacillus acidophilus) and bifidobacteria. These strains, usually derived from the human gut, were the starting point for probiotic research and application, and have played an important role in improving intestinal health.\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1e86aaf elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"1e86aaf\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p><strong><b>Key features<\/b><\/strong><\/p><p>The first generation of probiotics produce lactic acid through fermentation, which lowers the pH level in the intestines, thus inhibiting the growth of harmful bacteria and helping to maintain the micro-ecological balance of the intestines. They act on the intestines with a simple mechanism and belong to the initial stage of probiotic development.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1709ea6 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"1709ea6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p><strong><b>Efficacy<\/b><\/strong><\/p><p>First-generation probiotics offer a variety of health benefits, including:<\/p><ul><li><b><\/b><strong><b>improve digestion<\/b><\/strong>: Helps break down food and promotes nutrient absorption.<\/li><li><b><\/b><strong><b>strengthen immunity<\/b><\/strong>: Supports immune system function by regulating the gut microbiota.<\/li><li><b><\/b><strong><b>Prevention of intestinal problems<\/b><\/strong>: such as diarrhea and constipation, relieving intestinal discomfort. In addition, they produce vitamins (e.g., B vitamins) and enzymes that further promote good health.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06b1dd8 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"06b1dd8\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p><strong><b>Historic significance<\/b><\/strong><\/p><p>The first generation of probiotics laid the foundation for probiotic research and applications. Although subsequent generations of probiotics have become more diverse in function and application, the discovery and use of first-generation probiotics has provided valuable lessons and insights into these advances. In conclusion, first-generation probiotics are early probiotic strains, represented by Lactobacillus and Bifidobacterium, that function by regulating the intestinal environment and are important for human health.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0900bc2 e-con-full e-flex e-con e-child\" data-id=\"0900bc2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d5e039f elementor-invisible elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"d5e039f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-3-800x600.jpeg\" class=\"attachment-800x600 size-800x600\" alt=\"What are first generation probiotics?\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d028a6 elementor-invisible elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"1d028a6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u9759\u8c27\u7684\u5927\u6cb3\uff0c\u9ec4\u660f-2-800x600.jpeg\" class=\"attachment-800x600 size-800x600\" alt=\"What are first generation probiotics?\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-e0fd486 e-flex e-con-boxed e-con e-parent\" data-id=\"e0fd486\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1e42c50 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"1e42c50\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Why is AKK bacteria the star of second generation probiotics?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1dbbbf elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"b1dbbbf\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-66adc13 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"66adc13\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\tAKK bacteria (Akkermansia muciniphila) is regarded as the star of second generation probiotics, mainly because it has demonstrated a unique and important role in intestinal health, metabolic regulation, and the prevention of many diseases. Here are the specific reasons why:\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-ee7a876 e-flex e-con-boxed e-con e-parent\" data-id=\"ee7a876\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4f31093 e-con-full e-flex e-con e-child\" data-id=\"4f31093\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-594e518 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"594e518\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">1. Close association with metabolic diseases<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1006de elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"b1006de\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li>AKK bacteria are closely associated with the onset and development of metabolic diseases such as obesity, diabetes, and cardiovascular disease. It has been found that people with higher abundance of AKK bacteria in their bodies are usually in a healthier metabolic state, while reduced AKK bacteria are associated with problems such as obesity and insulin resistance.<\/li><li>It provides important support for the prevention and amelioration of metabolic diseases by regulating energy metabolism and improving insulin sensitivity.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c972cad e-con-full e-flex e-con e-child\" data-id=\"c972cad\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-951b9ee wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"951b9ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">2. Maintenance of intestinal barrier function<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0505ee elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"c0505ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li>AKK bacteria are able to break down mucus in the intestines and promote the renewal and maintenance of the mucus layer, thus enhancing the intestinal barrier function. This effectively prevents the invasion of harmful substances and pathogens and reduces the risk of intestinal inflammation.<\/li><li>This property allows AKK bacteria to play a key role in the prevention of gut-related diseases such as inflammatory bowel disease.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-c5b7668 e-flex e-con-boxed e-con e-parent\" data-id=\"c5b7668\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-36e6b64 e-con-full e-flex e-con e-child\" data-id=\"36e6b64\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9d590ed wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"9d590ed\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">3. Anti-inflammatory and immunomodulatory effects<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e9a532 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"3e9a532\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li>AKK bacteria have significant anti-inflammatory capacity, inhibiting the production of inflammatory factors and reducing the inflammatory response in the intestinal tract and other tissues.<\/li><li>It also regulates the immune system and helps maintain immune balance, which may be beneficial in preventing autoimmune diseases.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6e6d199 e-con-full e-flex e-con e-child\" data-id=\"6e6d199\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-613b5e6 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"613b5e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">4. Potential anti-tumor effects<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-212f505 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"212f505\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li>Recent studies have shown that AKK bacteria may positively impact the prevention and treatment of certain cancers by modulating the intestinal microecology and immune system, a potential that has further elevated its interest.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-49ea978 e-flex e-con-boxed e-con e-parent\" data-id=\"49ea978\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-774abf2 e-con-full e-flex e-con e-child\" data-id=\"774abf2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8e5c436 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"8e5c436\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">3. Anti-inflammatory and immunomodulatory effects<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bd517a8 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"bd517a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li>Compared to traditional probiotics such as Lactobacillus and Bifidobacterium, AKK bacteria, as second generation probiotics, show broader and deeper effects on metabolic health and intestinal barrier protection.<\/li><li>Its discovery has brought new breakthroughs in probiotic research, showing great application prospects.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dcd191d e-con-full e-flex e-con e-child\" data-id=\"dcd191d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5f310a7 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"5f310a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Summarize<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88fc4a1 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"88fc4a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>AKK bacteria have become the star bacteria in the second generation of probiotics due to their unique functions in metabolic regulation, intestinal barrier maintenance, anti-inflammation, immunomodulation and potential anti-tumor effects. These properties not only make it significant in maintaining health, but also make it attract the attention of scientific research and medical community, with broad development potential.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-ca22579 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"ca22579\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-bbd04cb e-con-full e-flex e-con e-child\" data-id=\"bbd04cb\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-96f0009 wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"96f0009\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">To date, are there any second-generation probiotics which have been approved for marketing in China?<br \/>\nWhat is the worldwide availability?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9346f30 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"9346f30\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ee3cb3 elementor-widget elementor-widget-wd_text_block\" data-id=\"7ee3cb3\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>As of April 2020, China approved 137 health food products with probiotics as the main ingredient, and no second-generation efficacious probiotics have yet been approved for marketing in China.<\/p><p>Since its discovery in 2004, more than 20 years of laboratory and clinical research on AKK bacteria, a large number of scientific and clinical data to prove its safety and effectiveness, in 2022, the European Union and the United States, successively approved the commercialization of AKK bacteria products for sale.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ab0b624 e-con-full e-flex e-con e-child\" data-id=\"ab0b624\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8aa44e2 elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"8aa44e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1.jpeg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1.jpeg 1024w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1-300x300.jpeg 300w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1-150x150.jpeg 150w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1-600x600.jpeg 600w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1-768x768.jpeg 768w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u5065\u5eb7\u751f\u6d3b\uff0c\u7eff\u8272\u98df\u7269-1-45x45.jpeg 45w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-fbe38e8 wd-section-stretch e-flex e-con-boxed e-con e-parent\" data-id=\"fbe38e8\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7c54b31 wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"7c54b31\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What are the main benefits of scientifically proven AKK bacteria?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-74ced14 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"74ced14\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\t<p>AKK bacteria (mucinophilic Ackermannia.<em><i>Akkermansia muciniphila<\/i><\/em>) has received much attention in recent years in the field of gut health and metabolic regulation. Below are the key scientifically proven effects of AKK bacteria, and the specific sources of the leading journals and academic conferences where this evidence has been published:<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-b9a732c e-grid e-con-boxed e-con e-parent\" data-id=\"b9a732c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1641cf2 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"1641cf2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b8c718 elementor-widget elementor-widget-wd_infobox\" data-id=\"9b8c718\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t01\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tImproved metabolic health\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria are negatively associated with obesity, diabetes, cardiovascular metabolic disease and low-grade inflammation. Studies have shown that oral administration of AKK bacteria improves metabolic disease symptoms in mice.<\/li>\n<li><b><\/b><strong><b>evidence<\/b><\/strong>\uff1a\n<ul>\n<li>A 2013 study found that AKK bacteria counts were significantly reduced in obese and type II diabetic mice and that symptoms improved with AKK bacteria supplementation.<\/li>\n<li>Early High-Fat Diet Affects Learning and Cognitive Function in Mice by Reducing AKK Bacteria Abundance, Associated with Metabolic Health, 2019 Study Shows<\/li>\n<li>In 2022, the European Commission approved the use of pasteurization-inactivated AKK bacteria to be placed on the market as a novel food product, demonstrating its potential application in metabolic health.<\/li>\n<\/ul>\n<\/li>\n<li><b><\/b><strong><b>source<\/b><\/strong>\uff1a\n<ul>\n<li>Neuropsychopharmacology (2019)<\/li>\n<li>European Commission Regulation (EU) 2022\/168<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4629daf e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"4629daf\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f5a8f29 elementor-widget elementor-widget-wd_infobox\" data-id=\"f5a8f29\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t02\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tRegulating the immune system\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria have a potential function in inflammatory bowel disease (IBD) to reduce symptoms of enteritis, modulate the immune response, and potentially prevent bowel cancer.<\/li>\n<li><b><\/b><strong><b>evidence<\/b><\/strong>\uff1a\n<ul>\n<li>Research from Nanjing Medical University found that oral administration of inactivated AKK bacteria or its outer membrane protein Amuc_1100 can improve colitis symptoms and has the effect of preventing bowel cancer.<\/li>\n<li>The German Cancer Research Center (DKFZ) has found that increasing the concentration of AKK bacteria in a mouse model of acromegaly (ALS) improves symptoms and prolongs survival.<\/li>\n<\/ul>\n<\/li>\n<li><b><\/b><strong><b>source<\/b><\/strong>\uff1a\n<ul>\n<li>Neuropsychopharmacology (2019)<\/li>\n<li>German Cancer Research Center (DKFZ) Study<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7289b92 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"7289b92\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c375714 elementor-widget elementor-widget-wd_infobox\" data-id=\"c375714\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t03\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tAnti-obesity and diabetes\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria ameliorate high-fat diet-induced intestinal mucosal barrier dysfunction and metabolic disorders.<\/li>\n<li><b><\/b><strong><b>evidence<\/b><\/strong>\uff1a\n<ul>\n<li>Supplementation of AKK bacteria by gavage significantly improved the symptoms of metabolic disorders in mice on a high-fat diet.<\/li>\n<li>In a mouse model of type II diabetes, the combination of AKK bacteria and metformin enhanced the therapeutic effect.<\/li>\n<\/ul>\n<\/li>\n<li><b><\/b><strong><b>source<\/b><\/strong>\uff1a<\/li>\n<\/ul>\n<p>\u300aProceedings of the National Academy of Sciences\u300b\uff08\u300aPNAS\u300b\uff09<\/p>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f3b402 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"6f3b402\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4ea8cd3 elementor-widget elementor-widget-wd_infobox\" data-id=\"4ea8cd3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t04\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tImprovement of cognitive function\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria are associated with cognitive dysfunction and supplementation with AKK bacteria may help improve cognitive function.<\/li>\n<li><b><\/b><strong><b>evidence<\/b><\/strong>\uff1a\n<ul>\n<li>A study by a team from Chengdu University of Traditional Chinese Medicine found that an early high-fat diet affected learning and cognitive function in mice by decreasing the abundance of AKK bacteria, and that the symptoms improved after supplementation with AKK bacteria.<\/li>\n<\/ul>\n<\/li>\n<li><b><\/b><strong><b>source<\/b><\/strong>\uff1a\n<ul>\n<li>Neuropsychopharmacology (2019)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-851207a e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"851207a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1443271 elementor-widget elementor-widget-wd_infobox\" data-id=\"1443271\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t05\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\textend life\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria are more abundant in the intestines of long-lived elderly people, and supplementation with AKK bacteria may help prolong life.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-85d7af3 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"85d7af3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5ff183a elementor-widget elementor-widget-wd_infobox\" data-id=\"5ff183a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t06\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tImprovement of intestinal barrier function\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria enhance intestinal barrier function and reduce intestinal permeability.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2f65ed5 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"2f65ed5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cc05abb elementor-widget elementor-widget-wd_infobox\" data-id=\"cc05abb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t07\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tRegulates intestinal flora\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria can regulate the composition of intestinal flora and maintain intestinal ecological balance.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1177b68 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"1177b68\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b8da712 elementor-widget elementor-widget-wd_infobox\" data-id=\"b8da712\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t08\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tanti-inflammatory effect\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria are anti-inflammatory and reduce inflammatory reactions.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-165d8da e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"165d8da\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-84cfafd elementor-widget elementor-widget-wd_infobox\" data-id=\"84cfafd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t09\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tImproving Autism Symptoms\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria may be associated with improved autism symptoms.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2dd5ed3 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"2dd5ed3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6dc1bee elementor-widget elementor-widget-wd_infobox\" data-id=\"6dc1bee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\t\t\t\t\t<div class=\"box-icon-wrapper  box-with-text text-size-small box-icon-with-bg\">\n\t\t\t\t\t\t<div class=\"info-box-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t10\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h4\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\tImprovement of fatty liver\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Efficacy<\/b><\/strong>: AKK bacteria may help improve non-alcoholic fatty liver disease (NAFLD).<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-489ecb3 e-flex e-con-boxed e-con e-parent\" data-id=\"489ecb3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c3b502b wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"c3b502b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">What is the best way to choose between the live (prebiotic) and inactivated (postbiotic) types of AKK products?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bd1b3e6 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"bd1b3e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48582c6 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"48582c6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\tAkkermansia muciniphila (hereinafter referred to as Akk bacteria) is a beneficial bacterium found in the human gut that has gained attention for its potential to improve metabolic health and enhance intestinal barrier function. Regarding whether to choose inactivated bacteria (usually referred to as pasteurized organisms) or live bacteria when supplementing with Akk bacteria, the following is a comparison of four aspects: benefits, scientific basis, risks, and mechanism of action.\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-4a8da57 e-flex e-con-boxed e-con e-parent\" data-id=\"4a8da57\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-957dfab e-con-full e-flex e-con e-child\" data-id=\"957dfab\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f68df71 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"f68df71\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-primary wd-title-style-underlined wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Inactivated bacteria (pasteurized Akk bacteria)<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d2fb96 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"8d2fb96\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\t<p><strong><b>Benefit<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Improvement of metabolic parameters<\/b><\/strong>: Studies have shown that pasteurized Akk bacteria can boost insulin sensitivity and lower cholesterol levels, which is especially beneficial for obese and overweight people.<\/li><li><b><\/b><strong><b>Strengthening the intestinal barrier<\/b><\/strong>: Promotes improved intestinal barrier function through its structural components that interact with the host.<\/li><\/ul><p><strong><b>Scientific basis<\/b><\/strong><\/p><ul><li>A human study (Depommier et al., 2019) found that pasteurized Akk bacteria were more effective than live bacteria in improving certain metabolic markers, such as insulin sensitivity.<\/li><li>Animal studies (e.g., Plovier et al., 2017) have also shown that pasteurized Akk bacteria significantly improve metabolic health, with effects not even inferior to those of live bacteria.<\/li><\/ul><p><strong><b>Risks<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Lower risk<\/b><\/strong>: The safety profile is high because inactivated bacteria cannot colonize the gut or cause infection. No serious adverse reactions were reported in the study and it was well tolerated.<\/li><\/ul><p><strong><b>Mechanisms<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Immune regulation<\/b><\/strong>: Regulates immune responses primarily through the interaction of bacterial structural components (e.g., outer membrane protein Amuc_1100) with host immune receptors (e.g., TLR2).<\/li><li><b><\/b><strong><b>Improvement of the intestinal barrier<\/b><\/strong>: These ingredients enhance the integrity of the intestinal mucus layer and indirectly improve metabolic health.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a8f51de e-con-full e-flex e-con e-child\" data-id=\"a8f51de\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e5de52b wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"e5de52b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-primary wd-title-style-underlined wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Live bacteria (live Akk bacteria)<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d1d3e4 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"6d1d3e4\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\t<p><strong><b>Benefit<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Improved metabolic health<\/b><\/strong>: Live bacteria improve metabolic disorders, enhance intestinal barrier function and reduce inflammation.<\/li><li><b><\/b><strong><b>Regulates intestinal ecology<\/b><\/strong>: Produces beneficial substances through metabolic activity and interacts with other gut microbes.<\/li><\/ul><p><strong><b>Scientific basis<\/b><\/strong><\/p><ul><li>Animal studies have shown that live Akk bacteria improve metabolic status, enhance the gut barrier and reduce inflammation levels in obese mice.<\/li><li>There are fewer human studies, but preliminary evidence suggests a similar potential, although the effect may not be as dramatic as in pasteurized forms.<\/li><\/ul><p><strong><b>Risks<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Theoretical risk<\/b><\/strong>: In immunocompromised populations, there may be a risk of overgrowth or triggering adverse reactions from live bacteria, but there is no evidence that Akk bacterial supplementation is harmful and is generally considered safe.<\/li><\/ul><p><strong><b>Mechanisms<\/b><\/strong><\/p><ul><li><b><\/b><strong><b>Mucin degradation<\/b><\/strong>: Live bacteria degrade intestinal mucin, stimulate new mucus production and strengthen the intestinal barrier.<\/li><li><b><\/b><strong><b>Short-chain fatty acids (SCFAs) production<\/b><\/strong>: Produces metabolites such as acetic acid and propionic acid, which have anti-inflammatory properties and provide energy to intestinal cells.<\/li><li><b><\/b><strong><b>Immune regulation<\/b><\/strong>: Interacts directly with host immune cells to modulate the immune response.<\/li><li><b><\/b><strong><b>Microbiota regulation<\/b><\/strong>: Promote a healthy microbial ecology through dynamic interactions with other gut flora.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-89ef240 e-flex e-con-boxed e-con e-parent\" data-id=\"89ef240\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b66f37 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"9b66f37\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Summarize and compare<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-50f1ae8 e-flex e-con-boxed e-con e-parent\" data-id=\"50f1ae8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-18511fc e-con-full e-flex e-con e-child\" data-id=\"18511fc\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ad2237c wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"ad2237c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Inactivated bacteria (pasteurized Akk bacteria)<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5436a5c elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"5436a5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li><b><\/b><strong><b>Advantages<\/b><\/strong>: Based on existing research, it is more effective in improving metabolic health and less risky due to its inability to reproduce. Pasteurization also makes it more stable and easier to produce and store.<\/li><li><b><\/b><strong><b>Applicable Scenarios<\/b><\/strong>: Ideal for supplemental needs that seek security and stability.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f7636a1 e-con-full e-flex e-con e-child\" data-id=\"f7636a1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e110728 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"e110728\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Live bacteria (live Akk bacteria)<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e43ed3e elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"e43ed3e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ul><li><b><\/b><strong><b>Advantages<\/b><\/strong>: May provide additional benefits through metabolic activity and dynamic regulation, especially in intestinal ecological regulation.<\/li><li><b><\/b><strong><b>Applicable Scenarios<\/b><\/strong>: For those who can tolerate live bacteria and want the full range of benefits.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f4ce0ab e-con-full e-flex e-con e-child\" data-id=\"f4ce0ab\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-16ca7f5 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"16ca7f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">current state of science<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b5c977 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"5b5c977\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Current evidence slightly favors the advantage of pasteurized Akk bacteria in metabolic improvement, but live bacteria also have their own unique role. More research is still needed to validate the long-term effects and optimal application of both.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-8b6d0d4 e-flex e-con-boxed e-con e-parent\" data-id=\"8b6d0d4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ea77a0 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"9ea77a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\t<p>In summary, the choice of inactivated or live bacteria depends on specific needs: if safety and metabolic improvement are important, pasteurized Akk bacteria may be preferable.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-ffc4fc4 e-flex e-con-boxed e-con e-parent\" data-id=\"ffc4fc4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b5faf8 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"3b5faf8\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Why Amcu_1100 content is the most important indicator for judging inactivated bacterial AKK products<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d6ee102 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"d6ee102\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-931ea8f elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"931ea8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-center\">\n\t\t\t\n\t\t\tThe level of Amuc_1100 is considered the most important indicator when judging inactivated bacterial AKK (Akkermansia muciniphila) products for several key reasons:\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-7df25be e-grid e-con-boxed e-con e-parent\" data-id=\"7df25be\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-420dec3 e-con-full e-flex e-con e-child\" data-id=\"420dec3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e3b79fb wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"e3b79fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">1. Amuc_1100 is the key active ingredient<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-743a89a elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"743a89a\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Amuc_1100 is an outer membrane protein of AKK bacteria that plays a central role in inactivating the bacteria. It has been shown that Amuc_1100 is able to interact with host immune receptors (e.g. TLR2) to modulate the immune response. This action can:<\/p><ul><li>Improved metabolic health, such as increased insulin sensitivity and lower cholesterol levels;<\/li><li>Enhances intestinal barrier function and protects intestinal health.<\/li><\/ul><p>For example, the study by Depommier et al. (2019) found that the effect of pasteurized AKK bacteria (i.e., inactivated bacteria) in improving metabolic parameters was strongly correlated with the presence of Amuc_1100, which underscores its importance.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4c3ba3b e-con-full e-flex e-con e-child\" data-id=\"4c3ba3b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a7b6553 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"a7b6553\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">2. Dependence of inactivating bacteria on structural components<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49eacd4 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"49eacd4\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Unlike live bacteria, inactivated bacteria are unable to colonize or produce metabolites in the intestinal tract, so their benefits are largely dependent on the structural components of the bacterium itself, of which Amuc_1100 is the most critical part. Key features include:<\/p><ul><li><b><\/b><strong><b>Stability<\/b><\/strong>: Amuc_1100 is able to remain stable and not easily degraded during the inactivation process, which ensures the activity of the product during production, storage and use.<\/li><li><b><\/b><strong><b>Direct effect<\/b><\/strong>: Since inactivated bacteria are unable to dynamically regulate the intestinal environment, Amuc_1100 becomes the main material basis for its efficacy.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e5d4ca1 e-con-full e-flex e-con e-child\" data-id=\"e5d4ca1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be4b7e2 wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"be4b7e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">3. Scientific evidence supporting the efficacy of Amuc_1100<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-246d48f elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"246d48f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Several studies have provided a rationale for the importance of Amuc_1100:<\/p><ul><li>Animal experiments (Plovier et al., 2017) showed that purified Amuc_1100 protein was able to mimic some of the benefits of inactivating AKK bacteria, demonstrating that it is the key active ingredient.<\/li><li>Human studies have shown that inactivated AKK bacteria are even more effective than live bacteria in improving metabolic health, further emphasizing the role of Amuc_1100.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ca617c0 e-con-full e-flex e-con e-child\" data-id=\"ca617c0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d61453e wd-width-100 elementor-invisible elementor-widget elementor-widget-wd_title\" data-id=\"d61453e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">4. Content directly determines product effectiveness<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a1c53d7 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"a1c53d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>The level of Amuc_1100 directly affects the efficacy of inactivated bacteria products:<\/p><ul><li><b><\/b><strong><b>Dose effect<\/b><\/strong>: The higher the content, the greater the product's potential to modulate immune response, improve metabolic health and strengthen the intestinal barrier.<\/li><li><b><\/b><strong><b>Quality assessment<\/b><\/strong>: Therefore, the content of Amuc_1100 has become a central criterion for the quality and effectiveness of inactivated AKK bacterial products.<\/li><\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-eacf47f e-flex e-con-boxed e-con e-parent\" data-id=\"eacf47f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0678fae e-con-full e-flex e-con e-child\" data-id=\"0678fae\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e571281 elementor-invisible elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"e571281\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u7eff\u8272\u5065\u5eb7\u751f\u6d3b\uff0c\u6d3b\u529b\u8fd0\u52a8-800x600.jpeg\" class=\"attachment-800x600 size-800x600\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d2f1766 e-con-full e-flex e-con e-child\" data-id=\"d2f1766\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6308e50 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"6308e50\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>Amuc_1100 is regarded as the most important indicator for judging inactivated AKK bacteria products because it is the key ingredient for the benefits of inactivated bacteria, is stable and well supported by scientific research. At the same time, its content directly determines the effectiveness of the product. When evaluating an inactivated AKK bacterial product, focusing on the amount of Amuc_1100 most accurately reflects its potential health benefits.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-9cf3fe1 wd-section-stretch e-flex e-con-boxed e-con e-parent\" data-id=\"9cf3fe1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a95629f wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"a95629f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Why is the P9 protein the most important indicator when choosing a live Akk bacteria product? What are the risks of live bacteria products?<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-909d422 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"909d422\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-44f875f wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"44f875f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-primary wd-title-style-underlined wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">I. Core role and mechanism of P9 protein<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d9af100 e-grid e-con-full e-con e-child\" data-id=\"d9af100\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-a2e930d e-con-full e-flex e-con e-child\" data-id=\"a2e930d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-612d9de elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"612d9de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c25a519 elementor-widget elementor-widget-wd_infobox\" data-id=\"c25a519\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t1. Activation of the GLP-1 signaling pathway to regulate metabolism\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Role of GLP-1<\/b><\/strong>: Glucagon-like peptide-1 (GLP-1) is a hormone secreted by the intestines that suppresses appetite, promotes insulin secretion, and inhibits fat synthesis, making it a key target for glycemic control and weight loss.<\/li>\n<li><b><\/b><strong><b>Role of the P9 protein<\/b><\/strong>: The P9 protein binds to the surface of intestinal cells through the<strong><b>ICAM-2 receptor<\/b><\/strong>, triggering calcium signaling and activating GLP-1 secretion (requires IL-6 assistance). The P9 protein was shown to stimulate GLP-1 much more effectively than other proteins of Akk bacteria (e.g., Amuc_1100), and was the central driver of metabolic improvement.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a5dc2f e-con-full e-flex e-con e-child\" data-id=\"3a5dc2f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f6cfec3 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"f6cfec3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-114d9db elementor-widget elementor-widget-wd_infobox\" data-id=\"114d9db\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t2. Activates brown adipose tissue (BAT) to promote fat burning\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li class=\"translation-block\">P9 protein activates<strong><b> AMPK<\/b><\/strong> through the GLP-1 signaling pathway and promotes the expression of<strong><b> UCP1 protein <\/b><\/strong>in brown adipose tissue (BAT), which converts energy from white fat into calories for consumption (thermogenesis). Supplementation of high-fat diet mice with Akk bacteria resulted in a significant increase in temperature and heat production in interscapular BAT and a decrease in white fat.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0633a59 e-con-full e-flex e-con e-child\" data-id=\"0633a59\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27eb390 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"27eb390\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-538fe6e elementor-widget elementor-widget-wd_infobox\" data-id=\"538fe6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t3. Live bacteria dependence\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>It is the live bacteria that continue to secrete the P9 protein<\/b><\/strong>: Only surviving Akk bacteria can consistently produce P9 protein in the gut, while inactivated (dead) bacteria may have inadequate or inactivated P9 protein release due to cell wall rupture. The study showed that GLP-1 secretion and BAT thermogenesis were significantly better in the live bacteria group than in the dead bacteria group.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-9d2f97b e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"9d2f97b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-773ebba wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"773ebba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-primary wd-title-style-underlined wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">II, P9 protein is a key indicator to distinguish the effect of the product<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ce2a984 e-grid e-con-full e-con e-child\" data-id=\"ce2a984\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-ab40e62 e-con-full e-flex e-con e-child\" data-id=\"ab40e62\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-07cf34c elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"07cf34c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-efc72a8 elementor-widget elementor-widget-wd_infobox\" data-id=\"efc72a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t1. Comparison with other proteins\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Amuc_1100 protein<\/b><\/strong>: Amuc_1100 is another key protein of Akk bacteria, whose main function is to repair the intestinal mucus barrier and inhibit inflammation, but its contribution to metabolic regulation (e.g., GLP-1 secretion) is much weaker than that of the P9 protein.<\/li>\n<li><b><\/b><strong><b>Limitations of dead bacteria<\/b><\/strong>: Although dead bacteria retain some of their functions (e.g., inhibition of DPP4 activity, reduction of inflammatory markers), their P9 protein activity may be impaired, leading to reduced metabolic regulation.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f615463 e-con-full e-flex e-con e-child\" data-id=\"f615463\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be61914 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"be61914\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88ff458 elementor-widget elementor-widget-wd_infobox\" data-id=\"88ff458\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t2. Direct correlation between product effect and P9 protein content\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li>The dose of P9 protein is positively correlated with GLP-1 secretion, and low doses can significantly improve metabolic markers. When choosing a live bacterial product, it is important to ensure that the strain is able to consistently secrete sufficient amounts of P9 protein.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-1031229 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"1031229\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b696128 wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"b696128\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-primary wd-title-style-underlined wd-title-size-default text-center\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">III. Potential risks of live bacterial products<\/h4> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-999bda7 e-grid e-con-full e-con e-child\" data-id=\"999bda7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1cdcbc6 e-con-full e-flex e-con e-child\" data-id=\"1cdcbc6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a46fc64 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"a46fc64\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b9754a0 elementor-widget elementor-widget-wd_infobox\" data-id=\"b9754a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t1. The issue of viable bacteria\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>\u8fd0\u8f93\u4e0e\u50a8\u5b58\u98ce\u9669<\/b><\/strong>: Live bacteria are sensitive to temperature and humidity, and improper production, transportation, or storage (e.g., not cold-chained) may result in the death of the strain and the inability to secrete the P9 protein.<strong><b>Need to choose products in capsule form (barrier to water oxygen and &gt;=10 billion viable bacteria count)<\/b><\/strong>, to ensure successful gut colonization.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c0891db e-con-full e-flex e-con e-child\" data-id=\"c0891db\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-491be66 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"491be66\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7617d1f elementor-widget elementor-widget-wd_infobox\" data-id=\"7617d1f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t2. Immune response and allergy risk\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Possible immune rejection in a small number of people<\/b><\/strong>: Some individuals may have an intestinal environment that is not suitable for Akk bacteria to colonize, or may have an allergic reaction (e.g., diarrhea, bloating) to the P9 protein.<\/li>\n<li><b><\/b><strong><b>Immunodeficient persons should be cautious<\/b><\/strong>: Live bacteria may over-proliferate in immunocompromised individuals; medical advice is required.<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7c14f08 e-con-full e-flex e-con e-child\" data-id=\"7c14f08\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-faf555e elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"faf555e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a064e8 elementor-widget elementor-widget-wd_infobox\" data-id=\"6a064e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t3. Risk of overdose\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Imbalance of intestinal flora<\/b><\/strong>: Excessive supplementation with Akk bacteria may inhibit the growth of other beneficial bacteria (e.g., Bifidobacteria, Lactobacilli), leading to a decrease in flora diversity.<\/li>\n<li><b><\/b><strong><b>Potential side effect<\/b><\/strong>: Some studies have pointed out that long-term high-dose intake may trigger<strong><b>Bowel spasms or indigestion<\/b><\/strong>(further clinical validation required).<b><\/b><\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-af14b43 e-con-full e-flex e-con e-child\" data-id=\"af14b43\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-304fc16 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"304fc16\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-dna\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M.1 494.1c-1.1 9.5 6.3 17.8 15.9 17.8l32.3.1c8.1 0 14.9-5.9 16-13.9.7-4.9 1.8-11.1 3.4-18.1H380c1.6 6.9 2.9 13.2 3.5 18.1 1.1 8 7.9 14 16 13.9l32.3-.1c9.6 0 17.1-8.3 15.9-17.8-4.6-37.9-25.6-129-118.9-207.7-17.6 12.4-37.1 24.2-58.5 35.4 6.2 4.6 11.4 9.4 17 14.2H159.7c21.3-18.1 47-35.6 78.7-51.4C410.5 199.1 442.1 65.8 447.9 17.9 449 8.4 441.6.1 432 .1L399.6 0c-8.1 0-14.9 5.9-16 13.9-.7 4.9-1.8 11.1-3.4 18.1H67.8c-1.6-7-2.7-13.1-3.4-18.1-1.1-8-7.9-14-16-13.9L16.1.1C6.5.1-1 8.4.1 17.9 5.3 60.8 31.4 171.8 160 256 31.5 340.2 5.3 451.2.1 494.1zM224 219.6c-25.1-13.7-46.4-28.4-64.3-43.6h128.5c-17.8 15.2-39.1 30-64.2 43.6zM355.1 96c-5.8 10.4-12.8 21.1-21 32H114c-8.3-10.9-15.3-21.6-21-32h262.1zM92.9 416c5.8-10.4 12.8-21.1 21-32h219.4c8.3 10.9 15.4 21.6 21.2 32H92.9z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-422341b elementor-widget elementor-widget-wd_infobox\" data-id=\"422341b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_infobox.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"info-box-wrapper\">\n\t\t\t<div class=\"wd-info-box text-left box-icon-align-top box-style-base color-scheme-\">\n\t\t\t\t\n\t\t\t\t<div class=\"info-box-content\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h5\t\t\t\t\t\tclass=\"info-box-title title box-title-style-default wd-fontsize-m\" data-elementor-setting-key=\"title\">\n\t\t\t\t\t\t\t\t4. Controversy over the efficacy of dead versus live bacteria\t\t\t\t\t\t<\/h5>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"info-box-inner reset-last-child\"data-elementor-setting-key=\"content\"><ul>\n<li><b><\/b><strong><b>Dead bacteria may be preferable<\/b><\/strong>: Inactivation of Akk bacteria (dead bacteria) is more effective in inhibiting DPP4 activity, reducing inflammation levels, and is not dependent on intestinal survival.<\/li>\n<li><b><\/b><strong><b>Selection Recommendations<\/b><\/strong>\uff1a\n<ul>\n<li class=\"translation-block\">If the goal is glycemic control, weight loss or metabolic activation, prioritize live bacteria (need to ensure P9 protein activity).<\/li>\n<li class=\"translation-block\">If the goal is anti-inflammatory or repairing the gut barrier, dead bacteria may be more appropriate.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-453352b e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"453352b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d539176 e-con-full e-flex e-con e-child\" data-id=\"d539176\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f2d4cac wd-width-100 elementor-widget elementor-widget-wd_title\" data-id=\"f2d4cac\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"title-wrapper wd-set-mb reset-last-child wd-title-color-default wd-title-style-default wd-title-size-default text-left\">\n\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h3 class=\"woodmart-title-container title wd-fontsize-l wd-underline-colored\">Scientific Advice on Selecting Live Bacteria Products<\/h3> \n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f04d67 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1f04d67\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 117 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M3,1.5C5,4.9,6,8.8,6,13s-1.7,8.1-5,11.5C0.3,21.1,0,17.2,0,13S1,4.9,3,1.5z M16,1.5c2,3.4,3,7.3,3,11.5s-1,8.1-3,11.5c-2-4.1-3-8.3-3-12.5S14,4.3,16,1.5z M29,1.5c2,4.8,3,9.3,3,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S27,4.9,29,1.5z M41.1,1.5C43.7,4.9,45,8.8,45,13s-1,8.1-3,11.5c-2-3.4-3-7.3-3-11.5S39.7,4.9,41.1,1.5zM55,1.5c2,2.8,3,6.3,3,10.5s-1.3,8.4-4,12.5c-1.3-3.4-2-7.3-2-11.5S53,4.9,55,1.5z M68,1.5c2,3.4,3,7.3,3,11.5s-0.7,8.1-2,11.5c-2.7-4.8-4-9.3-4-13.5S66,3.6,68,1.5z M82,1.5c1.3,4.8,2,9.3,2,13.5s-1,7.4-3,9.5c-2-3.4-3-7.3-3-11.5S79.3,4.9,82,1.5z M94,1.5c2,3.4,3,7.3,3,11.5s-1.3,8.1-4,11.5c-1.3-1.4-2-4.3-2-8.5S92,6.9,94,1.5z M107,1.5c2,2.1,3,5.3,3,9.5s-0.7,8.7-2,13.5c-2.7-3.4-4-7.3-4-11.5S105,4.9,107,1.5z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e59794 elementor-widget elementor-widget-wd_text_block\" data-id=\"4e59794\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<ol><li><b><\/b><strong><b>Clearly labeled P9 protein content<\/b><\/strong>: Select products that state the concentration of P9 protein or are assayed by metabolic activity (e.g., GLP-1 secretion capacity).<\/li><li><b><\/b><strong><b>Number of live bacteria \u226510 billion\/dose<\/b><\/strong>: Ensure that the number of live bacteria is sufficient to colonize the intestinal tract and that the activity of the strain is certified by third-party testing.<\/li><li><b><\/b><strong><b>Dosage form selection capsules<\/b><\/strong>: Avoid powder or liquid dosage forms to prevent inactivation of live bacteria by exposure to air and moisture.<\/li><li><b><\/b><strong><b>With Probiotics<\/b><\/strong>: Choose products containing prebiotics such as inulin and oligofructose to promote Akk bacteria proliferation and P9 protein secretion.<\/li><li><b><\/b><strong><b>Attention to storage conditions<\/b><\/strong>: Refrigerate or keep away from light to avoid high temperature environment to destroy the activity of live bacteria.<\/li><\/ol>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f0ab814 e-con-full e-flex e-con e-child\" data-id=\"f0ab814\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d09a92d elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"d09a92d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd.jpeg\" class=\"attachment-full size-full\" alt=\"Scientific Advice on Selecting Live Bacteria Products\" srcset=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd.jpeg 1024w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd-300x300.jpeg 300w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd-150x150.jpeg 150w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd-600x600.jpeg 600w, https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u5927\u7684\u5c71\u5ddd-768x768.jpeg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"wd-negative-gap elementor-element elementor-element-3204e53 e-flex e-con-boxed e-con e-parent\" data-id=\"3204e53\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-629e918 e-con-full e-flex e-con e-child\" data-id=\"629e918\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a18355e elementor-invisible elementor-widget elementor-widget-wd_image_or_svg\" data-id=\"a18355e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_image_or_svg.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"wd-image text-left\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/akkbio.com\/wp-content\/uploads\/2025\/03\/\u81ea\u7136\u98ce\u666f\uff0c\u8349\u539f\u51b0\u5ddd-1-800x600.jpeg\" class=\"attachment-800x600 size-800x600\" alt=\"Scientific Advice on Selecting Live Bacteria Products\" \/>\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ac10b8d e-con-full e-flex e-con e-child\" data-id=\"ac10b8d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bef4df6 elementor-invisible elementor-widget elementor-widget-wd_text_block\" data-id=\"bef4df6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"wd_text_block.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"wd-text-block reset-last-child text-left\">\n\t\t\t\n\t\t\t<p>P9 protein is the core indicator of the effect of Akk Mushroom live bacterial products, and its activity directly determines the strength of metabolic regulation (e.g. GLP-1 secretion, fat burning). However, the risks of live bacterial products include survival rate, immune response and overdose, which need to be avoided through scientific selection and standardized use. By prioritizing the P9 protein and live bacterial activity indicators in relation to your needs (glycemic control, anti-inflammatory or fat burning), you can maximize the benefits of your product.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\u79d1\u5b66\u8bc1\u636e AKM\/\u963f\u514b\u66fc\u751f\u7269 \u81ea2004<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_wpcom_ai_launchpad_about_page":false,"_wpcom_ai_launchpad_gallery_page":false,"_wpcom_ai_launchpad_contact_page":false,"_wpcom_ai_launchpad_events_page":false,"_wpcom_ai_launchpad_video_page":false,"_wpcom_ai_launchpad_portfolio_piece":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"footnotes":""},"class_list":["post-25","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":100,"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":1002,"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/pages\/25\/revisions\/1002"}],"wp:attachment":[{"href":"https:\/\/akkbio.com\/en\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}